Weight gain and antidepressants: Emotional eating, indifference and effects on appetite. [zFNehZbih]

Weight gain and antidepressants: Emotional eating, indifference and effects on appetite. [zFNehZbih]

Antidepressants such as SSRIs can cause weight gain in some people and weight loss in others. We explain how that works: 1. Weight loss is often about their effect of SSRIs on increasing indifference which may then reduce emotional eating. 2. Weight gain is with SSRIs is often about their effects on increasing someone's indifference in their food choices. This clip explains how SSRI/SNRI affect sensitivity: https://www.youtube.com/watch?v=u_7LwL5EmAs Other antidepressants like Tricyclic antidepressants and Mirtazapine can cause sedation because of their antihistamine effects on increasing appetite. Thats why some medications which cause drowsiness also cause increased appetite. SSRIs include aropax/paroxetine, zoloft/sertraline, prozac/fluoxetine, luvox/fluvoxamine, lexapro/escitalopram and cipramil/citalopram. The mostly interact with the SERT protein to increase serotonin residence in the synapse. They minimally affect the Histamine receptor. Tricyclic antidepressants (TCA) include endep/amitriptyline, anafranil/clomipromine, dothiepin, nortriptyline etc. Generally have significant effect on Serotonin and noradrenaline reuptake (SERT and NET) as well as hitting specific serotonin receptors (e.g. clomipramine avidly binds 5-HT2c and 5-HT6). They bind Alpha1 and potently bind H1. Mirtazepine (Avanza) is a tetracyclic antidepressant, also called a "noradrenergic and specific serotonergic antidepressant", but it's not very specific. While it has negligible effect on serotonin or noradrenaline reuptake (negligible SERT or NET effect) but strongly interacts with a number of other receptors including serotonergic 5-HT2C, 5-HT3, Alpha2A, Alpha2C and H1. more at www.thepsychcollecitve.com #emotionaleating #SSRI #weightgain Our content and interactions through comments are for informational purposes and do not represent clinical advise. Consult with your doctor regarding any medication matters or mental/physical health concerns. Website: https://www.thepsychcollective.com Free resources: https://www.thepsychcollective.com/resources/ Follow us on Facebook: https://facebook.com/thepsychcollective/ YouTube: https://youtube.com/c/thePSYCHcollective Instagram: https://www.instagram.com/thepsychcollectivedotcom/?hl=en LinkedIn: https://au.linkedin.com/company/the-psych-collective Quora: https://www.quora.com/profile/Al-Griskaitis Medium: https://medium.com/@al.griskaitis Substack: https://algriskaitis.substack.com/

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