↓ Levothyroxine absorption: Bile acid–binding agents (eg, cholestyramine) Iron, calcium, aluminum hydroxide Proton pump inhibitors, sucralfate ↑ TBG concentration: Estrogen replacement, oral contraceptives Tamoxifen ↓ TBG concentration: Androgens, glucocorticoids Anabolic steroids ↑ Thyroid hormone metabolism: Rifampin Phenytoin Carbamazepine

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Thyroid hormone (levothyroxine) interactions [cpLJffVWw]

Thyroid hormone (levothyroxine) interactions [cpLJffVWw]

↓ Levothyroxine absorption: Bile acid–binding agents (eg, cholestyramine) Iron, calcium, aluminum hydroxide Proton pump inhibitors, sucralfate ↑ TBG concentration: Estrogen replacement, oral contraceptives Tamoxifen ↓ TBG concentration: Androgens, glucocorticoids Anabolic steroids ↑ Thyroid hormone metabolism: Rifampin Phenytoin Carbamazepine

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